IRAQI MUSLIMS OF EASTERN UTTAR PRADESH CONSIST OF ARAB AND DISTINCT INDO-EUROPEAN PATRILINEAL LINEAGES IN INDIA

 

SUMMARY: The Iraqi Muslims of the Eastern Uttar Pradesh (U.P.) population group is thought to include the descendants of West Asian, Arab and Indo-European (i.e. Persian) ancestors with a possible coalescence time of 500-700 years as a Caste/or Biradri in India. Recent DNA tests on few individuals are consistent with distinct paternal R1a1 terminal clades, and the common ancestors between the distant families appears >10 generations ago. However, migration history and exact time of the most recent common ancestors (MRCAs) consistent with the living population has not been examined in any genetic variant study to date. The allele frequency from a cohort of this population needs investigation. As a result, one can comprehensively identify: 1) ethnic mix; MRCAs actual presence at 20-30 generations before in India, 2) the founder effect/0r genetic drift, if any, and 3) phylogenetic affiliation. This study in combination with the international HapMap Project on DNA from other Indian populations will help provide insight into autosomal recessive diseases linked to this group.