IRAQI MUSLIMS OF EASTERN UTTAR PRADESH CONSIST OF ARAB AND DISTINCT INDO-EUROPEAN PATRILINEAL LINEAGES IN INDIA
SUMMARY: The Iraqi Muslims of Eastern Uttar Pradesh (U.P.) population group is thought to include the descendants of West Asian, Arab and Indo-European (i.e. Persian) ancestors with a possible coalescence time of 500-700 years as a Caste/or Biradri in India. DNA tests on few individuals are consistent with distinct paternal R1a1 clades, and time of the recent ancestors between the distant families varies 10 to 15 generations earlier. However, migration history and exact time of the most recent common ancestors (MRCAs) consistent with the living population has not been examined in any genetic variant study to date. The allele frequency from a cohort of this population needs investigation. As a result, one can comprehensively identify: 1) ethnic mix; MRCAs actual presence at 20-30 generations earlier in India, 2) the founder effect or genetic drift in the evolution, and 3) phylogenetic affiliation. This study, in combination with the international HapMap Project on DNA from other Indian populations will also provide insight into autosomal recessive diseases linked to this group.